Vitamin A

(beta carotene)-this vitamin has a bit of a mixed "pedigree". Vitamin A is a fat-soluble vitamin, so it has the potential to accumulate in tissues and cause liver toxicity. Conversely, if an individual has difficulties with fat absorption, they may actually be deficient in Vitamin A. Alcohol can enhance the toxicity of Vitamin A. Elevated levels of Vitamin A are associated with an increased risk of hip fracture in women. On the other hand, Vitamin A is an antioxidant, neutralizing free radicals. There have been some studies which suggest that high levels of Vitamin A may increase the risk of certain cancers, including breast cancer and lung cancer. However, other studies have shown Vitamin A to be useful in combating cervical cancer. This condition has been correlated with infection by the human papilloma virus. Vitamin A is often recommended for children with autism. This may stem from work in Africa, which found that high doses of Vitamin A were useful in reducing the severity of measles viral infection. Subsequent work has shown that while Vitamin A is useful to help eradicate virus if there is a Vitamin A deficiency, it can actually promote viral transmission if there is no deficiency. This may explain some of the divergent results with the use of Vitamin A. In summary, caution should be used when considering the use of high doses of Vitamin A.

Related Articles

Nutrient Guidelines Warn Against Overuse of Vitamin A

Portland Press Herald, Jan. 10, 2001

All Trans-Retinoic Acid Selectively Down-Regulates Matrix MMp-9 and Up-Regulates Tissue Inhibitor of TIMP-1 in Human Bronchoalvelar Lavage Cells

Molecular Medicine 2001

Vitamin A Calibrates a Heart Clock, 24-7

Science News, July 14, 2001 - Vol. 160

Nutrition a Key to Better Health for Elderly

Long-Term Nutrient Intake and Early Age-Related Nuclear Lens Opacities

JAMA, Oct. 10, 2001 - Vol. 286, #14

Relationship of Serum x-tocopherol, Carotenoids and Retinol With the Risk of Breast Cancer

Nutrition Research 21 - 2001

Vitamin A and Hip Fractures linked

Cicle Reader # 81

Vitamin A trap

Bottom Line health June 2002

Alcohol and Vitamin A. Alcohol Health & Research World

internet

Alcohol and Liver-Alcohol Alert No. 19-1993

internet

The latest on unsafe vitamins

www.usaweekend.com

Zinc, Vitamin A Help Anti-TB Drugs Work Better

Reuters Health (04.0202) Wednesday April 03, 2002